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KMID : 1103920110170020087
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Korean Journal of Hepatology
2011 Volume.17 No. 2 p.87 ~ p.95
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Epidemiology and prevention of hepatitis B virus infection
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Kwon So-Young
Lee Chang-Hong
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Abstract
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Hepatitis B virus (HBV) infection has been a major global cause of morbidity and mortality. The recognition of the problem led to a worldwide effort to reduce transmission of HBV through routine infant vaccination. HBV infection is the most common cause of chronic liver diseases and hepatocellular carcinoma in Korea. After hepatitis B vaccine era, seroprevalence of hepatits B surface antigen is decreasing, particularly in children. Hepatitis B vaccine is remarkably safe and shows high immunogenicity. Universal childhood immunization with three doses of hepatitis B vaccine in the first year of life is a highly effective method for prevention and control of hepatitis B.
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KEYWORD
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Hepatitis B virus, Epidemiology, Vaccine, Prevention
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